BACKGROUND: Schistosomiasis is a disease caused by parasitic worms and more than 200 million people are infected worldwide.The emergence of resistance to the most commonly used drug, praziquantel (PZQ), makes the development of novel drugs an urgent task.3-oxoacyl-ACP reductase (OAR), a key enzyme involved in the fatty acid synthesis pathway, has b
A Herpes Simplex Virus Type 2 Deleted for Glycoprotein D Enables Dendritic Cells to Activate CD4+ and CD8+ T Cells
Herpes simplex virus type 2 (HSV-2) is highly prevalent in the human population producing significant morbidity, mainly because of the generation of genital ulcers and neonatal encephalitis.Additionally, HSV-2 infection significantly increases the susceptibility of the host to acquire HIV and promotes the shedding of the latter in the coinfected.De
The Serological Prevalence of Rabies Virus-Neutralizing Antibodies in the Bat Population on the Caribbean Island of Trinidad
Rabies virus (RABV) is the only lyssavirus known to be present within the Caribbean.The island of Trinidad, is richly diverse in chiropteran fauna and endemic for bat-transmitted rabies with low RABV isolation rates observed in this population.We aimed to determine the seroprevalence of rabies virus neutralizing antibodies (RVNA) in light of spatio
Effects of the Loss of Binocular and Motion Parallax on Static Postural Stability
Depth information is important for postural stability and is Solar Charge Controllers generated by two visual systems: binocular and motion parallax.The effect of each type of parallax on postural stability remains unclear.We investigated the effects of binocular and motion parallax loss on static postural stability using a virtual reality (VR) sys
A new interdisciplinary approach to the study of the origins of traditional polyphony
The article discusses a new model of the origins of choral singing in the context of human evolutionary history.Hominid interaction with predators is seen as a crucial force in the evolution of human morphology and behaviour.Group singing and dancing, with body painting Baby Bathtubs and the use of masks, are perceived as critical elements of the s